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The biocompatibility of Carbon nanotube MESH has
been demonstrated, and is ready to be engineered
into therapeutic delivery systems. Such marvels promise
to impact those stubborn medical conditions like
the $150 Billion/year problem of Diabetes. This revelation
was among the latest results in the area of biomedical
applications of nanotechnology that were presented
by Doctor David Loftus at the January monthly seminar
of the IEEE
San Francisco Bay Area Nanotechnology Council .
Dr. Loftus is a practicing Hematology Oncologist on the adjunct clinical faculty
of the Stanford University School
of Medicine . In addition, at NASA AMES Research Center he is
affiliated with both the Center
for Nanotechnology and the Live Sciences Division where he serves
as the Medical Director of Hematology Oncology Projects. He is uniquely positioned
to see the pieces of the promise coming together for the near term biomedical
applications of nanotechnology.
He described how specially engineered CNT mesh, dubbed "Bucky Paper," was
introduced into one of the body's most reactive environments without negative
consequences. Construction of millimeter sized vehicles from rolls of this
nano-engineered bucky paper are underway in order to house biochemicals or
live cells that would otherwise be rejected by the body's defenses. Insulin
delivery pumps, nerve growth guides, and chemotherapy torpedoes are examples
of macro-sized vehicles with macro-sized payloads that bucky paper enables.
The porous nature of the mesh allows nutrients to penetrate while shielding
its cargo from the likes of antibodies, or a tumor's defenses. Equally possible
are biosensors designed to detect specific protein sequences and facilitate
rapid diagnosis. Biocompatible Bucky Paper then enables our well known nano-sized
Carbon tubes to be conveniently transformed into a macro sized, and therefore
useful, medical application tool.
Today, MDs are particularly frustrated over the lengthy diagnostic methodology
which starts with a tissue biopsy and then adds lab microscopic analysis toward
a later completed diagnosis. Subsequent treatments may include chemotherapy
delivered indiscriminately to the entire circulatory system. But diseases like
coronary artery disease, diabetes, and many cancers largely affect the body
locally and have well defined biochemistries. Locally delivered nanotechnology
engineered substances hold the promise of providing in-situ detection and diagnosis
which then would be followed by localized treatment.
Pressed to guess at what and when these results will surface, Dr. Loftus
volunteered that the "dumbest applications will be first." For example, the
mechanical aspects of bucky paper could enable surface applications like
wound healing to be realized within five to seven years. Therapeutic delivery
may be up to ten years away. By his count there are at least 30 US companies
now developing nanotechnology engineered encapsulation schemes. Given that
innovation breeds innovation, biocompatible bucky paper may provide the boost
needed to shorten the time tables toward the solution of many of today's
medical challenges.
Contact:
Nick Massetti
nick@NMassettiConsulting.com
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