(PRWEB)
- Markham, ON (PRWEB) September 30, 2005 -- AlphaRx
Inc. (OTC BB:ALRX.OB - News) today announced that
it has completed the development of a novel antibiotic
formulation using its patent pending solid lipid nanoparticle delivery platform.
The new product is announced under the trade name Vansolin ™ . The active ingredient
is Vancomycin, a very powerful antibiotic used mainly in hospitals to treat
life threatening infectious disease such as hospital acquired pneumonia, ventilator
associated pneumonia and severe sepsis. Vansolin ™ is the Company"s fourth
product employing proprietary nanotechnology, a line of products which are
intended to increase the efficacy of the existing base drug compounds while
reducing their side effects.
Vancomycin was initially introduced over forty years
ago to treat evolving Penicillin-resistant strains
of Staphylococci. Vancomycin is now often employed
as the drug of last-resort, the final treatment option
that a physician has to eliminate a bacterial infection
resistant to other antibiotic drugs.
The Company believes that encapsulating Vancomycin
into a nanoparticle formulation may increase its
efficacy. According to published research papers,
in vitro uptake of Vancomycin nanoparticles by white
blood cells is 20 times greater than free drug. The
Company anticipates that in vivo, after IV infusion,
white blood cells will readily absorb Vansolin ™ nanoparticles
and transport them to the site of inflammation and
infection, thereby increasing the local concentration
of Vancomycin and ultimately increasing its bactericidal
effect.
The Company has previously announced and outlined
the clinical development strategy of Zysolin ™ ,
a novel antibiotic nanoparticle formulation indicated
for the treatment of hospital acquired pneumonia.
Vansolin ™ will be developed using the same clinical
development strategy. The Company expects to advance
Vansolin ™ into the clinical phase during the fourth
quarter of 2006.
About AlphaRx Inc. ( www.AlphaRx.com )
AlphaRx is an emerging biopharmaceutical company
utilizing proprietary drug delivery technology to
develop novel formulations of drugs that are insoluble
or poorly soluble in water or have yet to be administrable
to the human body with an acceptable delivery method.
The Company"s product candidates address various
pharmaceutical markets, including arthritis, tuberculosis,
ocular infection, ocular inflammation and hospital
acquired pneumonia.
Forward Looking Statements:
This release contains forward-looking statements
within the meaning and pursuant to the Safe Harbor
provisions of the Securities Litigation Reform Act
of 1995 and involve risks and uncertainties that
may individually or mutually impact the matters herein
described, including but not limited to product development
and acceptance, manufacturing, competition, regulatory
and/or other factors, which are outside the control
of the Company.
This press release is available on the company's
official on-line investor relations site for investor
commentary, feedback and questions. Investors are
asked to visit http://www.agoracom.com and
view the "AlphaRx" Investor Discussion and Contact
Forum. In addition, investors are asked to e-mail
all questions and correspondence.
Contact:
For more information, please contact:
Agora Investor Relations Corp.
Web: http://www.agoracom.com
Phone: 416-496-0496
Agora Investor Relations Corp.
Media Relations
416-496-0496
E-mail
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