| TROY,
N.Y., March 30 /PRNewswire/ -- Evident Technologies
introduced today a second generation Type 2 EviTag(TM)
luminescent label. The T2 EviTag has a proprietary natural
coating that provides increased flexibility, easier
use, wider applications and possible reduced testing
costs in biological assays and other types of life science
research.
"At Evident, we are practical pioneers developing
nanomaterials to meet real needs and solve real problems,"
said Clint Ballinger, CEO of Evident Technologies.
"Our customers need smaller, brighter, more flexible
fluorescing markers to enable more applications across
different life science market segments. Our T2 EviTags
meet these needs and reduce testing costs because
of their flexibility and adaptability. We see EviTags
as an enabling technology at the crossroads of nano
and bio."
EviTags are biologically-inert, conjugation-ready
fluorescent labels built around a base of the company's
EviDot(TM) quantum dots, which are semiconductor nanocrystals
coated with a variety of patented, water- stabilizing
surface treatments appropriate for a range of applications.
Type 1 EviTags feature robust and stable synthetic
materials which help withstand the rigors of testing.
Evident's new Type 2 EviTags offer additional benefits
because of their natural surface coating, brighter
fluorescence and smaller size, which makes them more
suitable for fluorescent resonance energy transfer
(FRET) work, live animal or in vivo imaging and molecular
targeting.
"The work we are doing with Evident's tags is
proving to be a first, critical stage in further exploring
the inner space of cells. Clearly, we value these
very bright probes as we hope to illuminate inner
space," said Dr. Carl Batt, Director Cornell
University-Ludwig Institute for Cancer Research Partnership,
Liberty Hyde Bailey Professor of Cornell University.
Dr. Jonathan R. Slotkin, of The Brigham and Women's
Hospital, Harvard Medical School said, "It has
been a pleasure working with Evident Technologies'
T2 EviTags in our preliminary studies labeling murine
neural progenitor cells for in vitro and in vivo experimentation.
We have found the T2 EviTags give robust fluorescent
signal, and are remarkably stable in our culture systems.
"
"In addition, we have found Evident's scientific
product development and staff to be exceedingly knowledgeable,
and we look forward to a continued strong working
relationship with them as we move further into the
use of quantum dots for in vivo transplantation experiments
with neural progenitor cells in both developmental
and injury models," said Dr. Slotkin.
"With their new coatings, T2 EviTags have smaller
hydrodynamic radii and have been demonstrated to be
efficient donors of energy transfer to acceptor dyes.
The use of quantum dots in these assays will reduce,
if not resolve, the laborious and time consuming data
processing that is currently required to correct the
bleed-through contamination between donor and acceptor
dyes, making it easier and more straightforward to
perform live-cell time-lapse FRET to assay the highly
dynamic and transient live cellular processes. Prior
to this, FRET has been hard to accomplish using traditional
fluorophores to assay dynamic events in live cells,"
said Dr. Margarida Barroso, Assistant Professor at
Albany Medical College.
Type 2 EviTags are available in seven colors from
Lake Placid Blue (490nm) to Maple Red-orange (620nm),
with conjugation-ready surfaces of amine, carboxyl
and non-functionalized surfaces. Evident also has
under development a new class of EviTags capable of
advanced deep tissue imaging, as illustrated. These
will be available for beta testing soon.
About Evident Technologies
Evident Technologies (http://www.evidenttech.com/)
is a pioneer in the development of advanced nanomaterials
engineered to enable the creation of advanced products
for numerous markets including life sciences, solid
state lighting, energy, security, telecommunications
and emergent nanotechnology markets. Evident works
with customers worldwide to fashion these advanced
materials into new products and is also a leading
commercial source for a wide range of quantum dot
material systems that offer advantages over traditional
semiconductors. For more information, visit http://www.evidenttech.com/.
Source:
Evident Technologies
CONTACT:
Steven Talbot, CMO, +1-518-273-6266, Evident Technologies,
stalbot@evidenttech.com
Web site: http://www.evidenttech.com/
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